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Levomepromazine

CAT: 0013-GTR19203649-02Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19203649-02Size:1 ml x 10 mM (in DMSO)
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Description
Levomepromazine is an aliphatic phenothiazine with antipsychotic properties, functioning as a multi-receptor antagonist and a calcium release inducer. It is utilized in research models for neurodegenerative diseases, inflammation, and pain, based on its documented neuroprotective and antiviral activities in experimental studies.
CAS Number
60-99-1
Product Name Alternative
Methotrimeprazine, Levomepromazine
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
99.15% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.04 mM) ; DMSO:30 mg/mL (91.33 mM)
Smiles
C ([C@@H] (CN (C) C) C) N1C=2C (SC=3C1=CC=CC3) =CC=C (OC) C2
Molecular Formula
C19H24N2OS
Molecular Weight
328.47
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Levomepromazine

Methotrimeprazine is a member of the class of phenothiazines that is 10H-phenothiazine substituted by a (2R)-3-(dimethylamino)-2-methylpropyl group and a methoxy group at positions 10 and 2 respectively. It has a role as an anticoronaviral agent, a non-narcotic analgesic, a phenothiazine antipsychotic drug, a serotonergic antagonist, a dopaminergic antagonist, a cholinergic antagonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor. It is a tertiary amine and a member of phenothiazines. It derives from a hydride of a 10H-phenothiazine.

CAS Number60-99-1
PubChem CID72287
IUPAC Name(2R)-3-(2-methoxyphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine
Molecular FormulaC19H24N2OS
Molecular Weight328.5
XLogP4.7
Topological Polar Surface Area41
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Heavy Atom Count23
Formal Charge0
Complexity378
SMILES
C[C@@H](CN1C2=CC=CC=C2SC3=C1C=C(C=C3)OC)CN(C)C
InChI
InChI=1S/C19H24N2OS/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21/h5-11,14H,12-13H2,1-4H3/t14-/m1/s1
InChIKey
VRQVVMDWGGWHTJ-CQSZACIVSA-N
Chemical Structure
2D Structure
2D structure of Levomepromazine
CAS: 60-99-1
CID: 72287
Formula: C19H24N2OS
MW: 328.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight328.5
XLogP34.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass328.16093457
Monoisotopic Mass328.16093457
Topological Polar Surface Area41 Ų
Heavy Atom Count23
Formal Charge0
Complexity378
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-B1693-01Levomepromazine
T60944-01(±) -Levomepromazine
MBS5803659(+/-)-Levomepromazine
HY-B1693R-01Levomepromazine (Standard)
T71773-01Levomepromazine Maleate
HY-19489S3-01(±) -Levomepromazine-d3
T13470-01(±)-Levomepromazine-d6
T778500Levomepromazine Dimer
OR1005695Levomepromazine (maleate)
AR-L06264-01Levomepromazine Hydrochloride

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