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LLY-283

CAT: 0013-GTR19203632-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203632-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LLY-283 is a potent, selective, and orally bioavailable inhibitor of the PRMT5:MEP50 complex, demonstrating high affinity with a Kd of 6 nM. It exhibits robust antitumor activity and is a valuable chemical probe for investigating PRMT5 biology in cancer research, both in cellular and animal models.
CAS Number
2040291-27-6
Product Name Alternative
Histone Methyltransferase, HistoneMethyltransferase, MEP50, LLY283, LLY-283, LLY 283, PRMT5
Field of Research
Epigenetics & Chromatin
Purity
98.79% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.68 mM) ; H2O:3.57 mg/mL (10.43 mM) ; DMSO:112.5 mg/mL (328.61 mM)
Smiles
[H][C@@]1 (O[C@H] ([C@H] (O) [C@@H]1O) n1ccc2c (N) ncnc12) [C@H] (O) c1ccccc1
Molecular Formula
C17H18N4O4
Molecular Weight
342.35
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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BA4815-5.1LLY-283
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A19754-50LLY-283 50mg
A19754-5LLY-283 5mg
A19754-100LLY-283 100mg
A19754-10LLY-283 10mg

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