Products for Research Use Only

LY341495

CAT: 0013-GTR19203604-02Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203604-02Size:1 mg
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Description
LY341495 is a potent and selective antagonist of group II metabotropic glutamate receptors (mGluR2/3) . It is widely used in neuroscience research to investigate receptor function in models of anxiety, depression, and schizophrenia, both in vitro and in vivo.
CAS Number
201943-63-7
Product Name Alternative
LY341495, LY-341495, LY 341495, mGluR-2, human, mGluR1, mGluR-3, human, mGluR-8, human
Field of Research
Neuroscience
Purity
98.53% (May vary between batches)
Solubility
H2O:< 0.1 mg/mL (insoluble) ; DMSO:5 mg/mL (14.15 mM)
Smiles
N[C@@] (CC1c2ccccc2Oc2ccccc12) ([C@H]1C[C@@H]1C (O) =O) C (O) =O
Molecular Formula
C20H19NO5
Molecular Weight
353.37
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

LY-341495

(1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-1-cyclopropanecarboxylic acid is a member of xanthenes.

CAS Number201943-63-7
PubChem CID9819927
IUPAC Nametrans-(1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]cyclopropane-1-carboxylic acid
Molecular FormulaC20H19NO5
Molecular Weight353.4
XLogP-0.2
Topological Polar Surface Area110
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Heavy Atom Count26
Formal Charge0
Complexity559
SMILES
C1[C@@H]([C@H]1[C@@](CC2C3=CC=CC=C3OC4=CC=CC=C24)(C(=O)O)N)C(=O)O
InChI
InChI=1S/C20H19NO5/c21-20(19(24)25,15-9-13(15)18(22)23)10-14-11-5-1-3-7-16(11)26-17-8-4-2-6-12(14)17/h1-8,13-15H,9-10,21H2,(H,22,23)(H,24,25)/t13-,15-,20-/m0/s1
InChIKey
VLZBRVJVCCNPRJ-KPHUOKFYSA-N
Chemical Structure
2D Structure
2D structure of LY-341495
CAS: 201943-63-7
CID: 9819927
Formula: C20H19NO5
MW: 353.4
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight353.4
XLogP3-0.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass353.12632271
Monoisotopic Mass353.12632271
Topological Polar Surface Area110 Ų
Heavy Atom Count26
Formal Charge0
Complexity559
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes