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MK-0343

CAT: 0013-GTR19203550-04Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203550-04Size:10 mg
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Description
MK0343 is an orally administered, non-sedating anxiolytic compound that acts as a subtype-selective partial agonist of the GABAA receptor. It is a valuable research tool for investigating anxiety mechanisms and testing anxiolytic efficacy in both in vitro binding assays and in vivo behavioral models.
CAS Number
233275-76-8
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
FC1=CC=CC (F) =C1C2=NN=C3C=C (C (=NN32) OCC4=NC=NN4C) C5CCC5
Molecular Formula
C19H17F2N7O
Molecular Weight
397.38
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Mrk-409

MRK-409 is a GABA-A receptor agonist.

CAS Number233275-76-8
PubChem CID22609888
IUPAC Name7-cyclobutyl-3-(2,6-difluorophenyl)-6-[(2-methyl-1,2,4-triazol-3-yl)methoxy]-[1,2,4]triazolo[4,3-b]pyridazine
Molecular FormulaC19H17F2N7O
Molecular Weight397.4
XLogP3
Topological Polar Surface Area83
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Heavy Atom Count29
Formal Charge0
Complexity561
SMILES
CN1C(=NC=N1)COC2=NN3C(=NN=C3C4=C(C=CC=C4F)F)C=C2C5CCC5
InChI
InChI=1S/C19H17F2N7O/c1-27-16(22-10-23-27)9-29-19-12(11-4-2-5-11)8-15-24-25-18(28(15)26-19)17-13(20)6-3-7-14(17)21/h3,6-8,10-11H,2,4-5,9H2,1H3
InChIKey
GOIFCXRIFSYPFG-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Mrk-409
CAS: 233275-76-8
CID: 22609888
Formula: C19H17F2N7O
MW: 397.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight397.4
XLogP33
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass397.14626452
Monoisotopic Mass397.14626452
Topological Polar Surface Area83 Ų
Heavy Atom Count29
Formal Charge0
Complexity561
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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