Products for Research Use Only
RegisterLogin

CDK12-IN-3

CAT: 0013-GTR19203484-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19203484-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CDK12-IN-3 is a potent and selective inhibitor of cyclin-dependent kinase 12 (CDK12) . It is a valuable research tool for investigating CDK12's role in transcription and DNA damage response, with applications in studying oncology and tumor biology in both cellular and animal models.
CAS Number
2220184-50-7
Product Name Alternative
CDK12, CDK12 IN 3, CDK12IN3, CDK-12-IN-3, CDK12-IN-3
Field of Research
Cell Biology, Signal Transduction
Purity
99.85% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.63 mM) ; DMSO:200 mg/mL (425.06 mM)
Smiles
CC (C) n1cnc2c (NCc3nc4ccc (F) c (F) c4[nH]3) nc (nc12) N1CCCC[C@H]1CCO
Molecular Formula
C23H28F2N8O
Molecular Weight
470.52
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Cdk12-IN-3
CAS Number2220184-50-7
PubChem CID134691746
IUPAC Name2-[(2S)-1-[6-[(4,5-difluoro-1H-benzimidazol-2-yl)methylamino]-9-propan-2-ylpurin-2-yl]piperidin-2-yl]ethanol
Molecular FormulaC23H28F2N8O
Molecular Weight470.5
XLogP3.4
Topological Polar Surface Area108
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count7
Heavy Atom Count34
Formal Charge0
Complexity677
SMILES
CC(C)N1C=NC2=C(N=C(N=C21)N3CCCC[C@H]3CCO)NCC4=NC5=C(N4)C=CC(=C5F)F
InChI
InChI=1S/C23H28F2N8O/c1-13(2)33-12-27-20-21(26-11-17-28-16-7-6-15(24)18(25)19(16)29-17)30-23(31-22(20)33)32-9-4-3-5-14(32)8-10-34/h6-7,12-14,34H,3-5,8-11H2,1-2H3,(H,28,29)(H,26,30,31)/t14-/m0/s1
InChIKey
KULPPFCRBINTBS-AWEZNQCLSA-N
Chemical Structure
2D Structure
2D structure of Cdk12-IN-3
CAS: 2220184-50-7
CID: 134691746
Formula: C23H28F2N8O
MW: 470.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight470.5
XLogP33.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count7
Exact Mass470.23541387
Monoisotopic Mass470.23541387
Topological Polar Surface Area108 Ų
Heavy Atom Count34
Formal Charge0
Complexity677
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19259479-01CDK12/13-IN-3
GTR19277078-01CDK12/13 ligand 3
GTR19188551CDK12-IN-6
GTR17896602-01CDK12 Antibody
GTR19188550-01CDK12-IN-5
GTR18241937-01CDK12 Antibody
GTR17924097-01CDK12 Antibody
GTR18589622-01CDK12 Antibody
GTR19203845-01CDK12-IN-E9
GTR19234203-01CDK12-IN-7

Alternative Products

CatalogName
VND18450-01CDK12-IN-3
T206377-01CDK12/13-IN-3
A19768-10CDK12-IN-3 10mg
A19768-100CDK12-IN-3 100mg
A19768-50CDK12-IN-3 50mg
A19768-1CDK12-IN-3 1mg
A19768-5CDK12-IN-3 5mg
HY-177786CDK12 ligand-3
A19768-25CDK12-IN-3 25mg
558113-01CDK12

Popular Products