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Defactinib hydrochloride

CAT: 0013-GTR19203436-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203436-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Defactinib hydrochloride is a potent and selective FAK inhibitor that suppresses autophosphorylation at Tyr397 in a time- and dose-dependent fashion. It is a valuable research tool for studying FAK's role in cancer cell migration, proliferation, and survival in both cellular and animal models of tumor progression.
CAS Number
1073160-26-5
Product Name Alternative
Defactinib Hydrochloride, FAK, VS 6063 Hydrochloride, VS6063 Hydrochloride, VS-6063 hydrochloride, VS-6063 Hydrochloride, PF 04554878 hydrochloride, PF 04554878 Hydrochloride, PF04554878 Hydrochloride, PF-04554878 Hydrochloride
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.75% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (41.14 mM) ; H2O:0.1 mg/mL (0.18 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (0.91 mM)
Smiles
Cl.CNC (=O) c1ccc (Nc2ncc (c (NCc3nccnc3N (C) S (C) (=O) =O) n2) C (F) (F) F) cc1
Molecular Formula
C20H22ClF3N8O3S
Molecular Weight
546.95
Storage Conditions
-20°C
Notes
For research use only.

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A4651-10Defactinib hydrochloride
HY-12289A-01Defactinib (hydrochloride)
HY-12289AR-01Defactinib (hydrochloride) (Standard)
A22003-100Defactinib hydrochloride 100mg
A22003-50Defactinib hydrochloride 50mg
A22003-25Defactinib hydrochloride 25mg
A22003-10Defactinib hydrochloride 10mg
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A22003-2Defactinib hydrochloride 2mg
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