Products for Research Use Only

RG-12525

CAT: 0013-GTR19203193-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203193-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RG-12525 is a potent, orally active antagonist of cysteinyl leukotriene receptors and an agonist of PPAR-γ, with species-specific utility for asthma research. It demonstrates nanomolar potency in inhibiting ligand-induced contractions in vitro and also modulates CYP3A4 activity.
CAS Number
120128-20-3
Product Name Alternative
LTE4, LTC4, LTD4, NID 525, NID525, NID-525, LeukotrieneReceptor, leukotriene D (LTD), Leukotriene Receptor, CYP3A4, PPARγ, RG12525, RG-12525, RG 12525
Field of Research
Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Purity
95.49% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.36 mM) ; DMSO:10 mg/mL (23.61 mM)
Smiles
N1=NNC (=N1) CC=2C=CC=CC2COC3=CC=C (OCC4=NC=5C=CC=CC5C=C4) C=C3
Molecular Formula
C25H21N5O2
Molecular Weight
423.47
Storage Conditions
-20°C
Notes
For research use only.

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