Products for Research Use Only

LOM612

CAT: 0013-GTR19202668-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19202668-01Size:1 ml x 10 mM (in DMSO)
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Description
LOM612 is a specific small molecule FOXO relocator that induces nuclear translocation of FOXO transcription factors, leading to downregulation of c-Myc and cyclin D1. This mechanism confers anti-proliferative activity in human cancer cell lines, supporting its use in oncology research for studying FOXO-mediated pathways in vitro.
CAS Number
2173232-79-4
Field of Research
Cell Biology
Smiles
O=C1C=2SN=C (C2C (=O) C=3C=CC=CC13) N (C) C
Molecular Formula
C13H10N2O2S
Molecular Weight
258.3
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

3-(Dimethylamino)benzo[f][1,2]benzothiazole-4,9-dione
CAS Number2173232-79-4
PubChem CID134821683
IUPAC Name3-(dimethylamino)benzo[f][1,2]benzothiazole-4,9-dione
Molecular FormulaC13H10N2O2S
Molecular Weight258.30
XLogP2.7
Topological Polar Surface Area78.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Heavy Atom Count18
Formal Charge0
Complexity385
SMILES
CN(C)C1=NSC2=C1C(=O)C3=CC=CC=C3C2=O
InChI
InChI=1S/C13H10N2O2S/c1-15(2)13-9-10(16)7-5-3-4-6-8(7)11(17)12(9)18-14-13/h3-6H,1-2H3
InChIKey
LMNFZYAIQJKFFX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-(Dimethylamino)benzo[f][1,2]benzothiazole-4,9-dione
CAS: 2173232-79-4
CID: 134821683
Formula: C13H10N2O2S
MW: 258.30
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight258.30
XLogP32.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Exact Mass258.04629874
Monoisotopic Mass258.04629874
Topological Polar Surface Area78.5 Ų
Heavy Atom Count18
Formal Charge0
Complexity385
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes