Products for Research Use Only
RegisterLogin

NCX 1000

CAT: 0013-GTR19202645-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19202645-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NCX 1000 is a nitric oxide (NO) -releasing derivative of ursodeoxycholic acid (UDCA) designed for liver-targeted delivery. It is utilized in research to investigate NO-mediated mechanisms in hepatic models, including studies on portal hypertension and liver fibrosis in both cellular and animal studies.
CAS Number
401519-96-8
Field of Research
Metabolism Research
Smiles
[H][C@@]12CC[C@H] ([C@H] (C) CCC (=O) Oc3ccc (\C=C\C (=O) OCCCCO[N+] ([O-]) =O) cc3OC) [C@@]1 (C) CC[C@@]1 ([H]) [C@@]2 ([H]) [C@@H] (O) C[C@]2 ([H]) C[C@H] (O) CC[C@]12C
Molecular Formula
C38H55NO10
Molecular Weight
685.84
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

No-ursodeoxycholic acid

NCX-1000 is under investigation in clinical trial NCT00414869 (Preliminary Efficacy and Tolerability of NCX-1000 After Repeated Oral Doses in Patients With Elevated Portal Pressure).

CAS Number401519-96-8
PubChem CID129628949
IUPAC Name[2-methoxy-4-[(E)-3-(4-nitrooxybutoxy)-3-oxoprop-1-enyl]phenyl] (4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
Molecular FormulaC38H55NO10
Molecular Weight685.8
XLogP8
Topological Polar Surface Area157
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count10
Rotatable Bond Count15
Heavy Atom Count49
Formal Charge0
Complexity1170
SMILES
C[C@H](CCC(=O)OC1=C(C=C(C=C1)/C=C/C(=O)OCCCCO[N+](=O)[O-])OC)[C@H]2CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3[C@H](C[C@H]5[C@@]4(CC[C@H](C5)O)C)O)C
InChI
InChI=1S/C38H55NO10/c1-24(28-10-11-29-36-30(16-18-38(28,29)3)37(2)17-15-27(40)22-26(37)23-31(36)41)7-13-35(43)49-32-12-8-25(21-33(32)46-4)9-14-34(42)47-19-5-6-20-48-39(44)45/h8-9,12,14,21,24,26-31,36,40-41H,5-7,10-11,13,15-20,22-23H2,1-4H3/b14-9+/t24-,26+,27-,28-,29+,30+,31+,36+,37+,38-/m1/s1
InChIKey
WTAVOESJEWSDJC-OBOLPPCUSA-N
Chemical Structure
2D Structure
2D structure of No-ursodeoxycholic acid
CAS: 401519-96-8
CID: 129628949
Formula: C38H55NO10
MW: 685.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight685.8
XLogP38
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count10
Rotatable Bond Count15
Exact Mass685.38259695
Monoisotopic Mass685.38259695
Topological Polar Surface Area157 Ų
Heavy Atom Count49
Formal Charge0
Complexity1170
Isotope Atom Count0
Defined Atom Stereocenter Count10
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19208133-01NCX-278
GTR19201072-01NCX 466
GTR19273244-01NCX-530
GTR19208132-01NCX-274
GTR19201073NCX 4040
GTR19196967-01NCX-6560
GTR17964644Ncx-6 Antibody
GTR17964709Ncx-9 Antibody
GTR17964586Ncx-7 Antibody
GTR19318047Kit 1000

Alternative Products

CatalogName
16053-01Polyethylene Glycol 1000 (PEG 1000)
165977Polythylene Glycol 1000 (PEG 1000)
T6788Trypsin/Chrmotrypsin Complex 1000:1000
24500-0.5PLA (1000) -b-PEG (1000) -b-PLA (1000), Triblock Polymer
sc-203182PEG 1000
2433500-01CryoGate 1000
HY-U00023NCX 1000
SP50001000-5000ul
C07080Cetomacrogol 1000
2433400CryoRelay 1000

Popular Products