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(±) -AMG 487

CAT: 0013-GTR19201530-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19201530-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AMG 487 is a potent and selective CXCR3 antagonist, effectively inhibiting IP-10, ITAC, and MIG-induced chemotaxis with IC50 values of 8, 15, and 36 nM, respectively. This small molecule is a valuable research tool for studying CXCR3 function in autoimmune diseases, transplant rejection, and cancer in both cellular and animal models.
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
CCOC1=CC=C (N2C (C (N (C (CC3=CC=C (OC (F) (F) F) C=C3) =O) CC4=CN=CC=C4) C) =NC5=C (C2=O) C=CC=N5) C=C1
Molecular Formula
C32H28F3N5O4
Molecular Weight
603.59
Storage Conditions
-20°C
Notes
For research use only.

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