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R-130823

CAT: 0013-GTR19210613-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210613-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
R-130823 is a potent and selective p38α MAPK inhibitor (IC50=22 nM) that suppresses pro-inflammatory cytokine release in vitro. It demonstrates significant in vivo efficacy by reducing established paw swelling and hyperalgesia in a rat adjuvant-induced arthritis model.
CAS Number
321344-32-5
Smiles
C (CC1=CC=CC=C1) N2CCC (C=3C (=C (NC3) C4=CC=C (F) C=C4) C=5C=CN=CC5) =CC2
Molecular Formula
C28H26FN3
Molecular Weight
423.52
Storage Conditions
-20°C
Notes
For research use only.

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