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ACY-957

CAT: 0013-GTR19206554-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206554-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ACY-957 (C001) is a potent, orally bioavailable small molecule that selectively inhibits HDAC1 and HDAC2 with IC50 values of 7 nM and 18 nM, respectively, while showing minimal activity against HDAC3 and other class I/II HDACs. This selectivity profile makes it a valuable chemical probe for epigenetic research in oncology and neurology, supporting both in vitro mechanistic studies and in vivo disease model investigations.
CAS Number
1609389-52-7
Product Name Alternative
HDAC3, HDAC1, HDAC Inhibitor C 001, HDAC Inhibitor C001, HDAC Inhibitor C-001, HDAC2, ACY 957, ACY957, ACY-957
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
98.24% (May vary between batches)
Solubility
DMSO:50 mg/mL (116.4 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.66 mM)
Smiles
Nc1ccc (cc1NC (=O) c1ccc2nc (ccc2c1) N1CCNCC1) -c1cccs1
Molecular Formula
C24H23N5OS
Molecular Weight
429.54
Storage Conditions
-20°C
Notes
For research use only.

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BA4125-5ACY-957
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