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CBS-3595

CAT: 0013-GTR19197944-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19197944-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CBS-3595 is a dual p38α MAPK/PDE-4 inhibitor with moderate nanomolar potency, favorable pharmacokinetics, and low plasma protein binding. Its anti-inflammatory efficacy, demonstrated by suppressing TNFα release in vivo, occurs at doses and systemic exposures significantly below toxicological thresholds, supporting its research utility in inflammatory disease models.
CAS Number
908380-97-2
Field of Research
Metabolism Research, Signal Transduction
Smiles
CN1C (=C (N=C1S (C) =O) C2=CC=C (F) C=C2) C=3C=C (NC (C) =O) N=CC3
Molecular Formula
C18H17FN4O2S
Molecular Weight
372.42
Storage Conditions
-20°C
Notes
For research use only.

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