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Fusidic acid

CAT: 0804-HY-B1350-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1350-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fusidic acid (Fusidate) a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid has no corticosteroid effects. Fusidic acid inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome. Fusidic acid holds promise for research in anticancer and anti-infective applications.[1][2][3][4][5].
CAS Number
6990-06-3
Product Name Alternative
Fusidate; SQ-16603
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/fusidic-acid.html
Purity
99.79
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@H]([C@]1([H])CC[C@]([C@@](C[C@@H]/2OC(C)=O)3C)4C)[C@H](O)CC[C@]1(C)[C@]4([H])[C@H](O)C[C@@]3([H])C2=C(C(O)=O)/CC/C=C(C)\C
Molecular Formula
C31H48O6
Molecular Weight
516.71
Precautions
H302, H315, H319, H335
References & Citations
[1]Curbete MM, et al. A Critical Review of the Properties of Fusidic Acid and Analytical Methods for Its Determination. Crit Rev Anal Chem. 2016;46 (4) :352-360.|[2]Payne AJ, et al. Fusidic acid is an effective treatment against Toxoplasma gondii and Listeria monocytogenes in vitro, but not in mice. Parasitol Res. 2013;112 (11) :3859-3863.|[3]Kim JY, et al. Growth inhibition by fusidic acid in cervical, thyroid, and breast carcinoma cell lines. Obstet Gynecol Sci. 2023 Mar;66 (2) :100-106.|[4]Lemaire S, et al. Activity of fusidic acid against extracellular and intracellular Staphylococcus aureus: influence of pH and comparison with linezolid and clindamycin. Clin Infect Dis. 2011 Jun;52 Suppl 7:S493-503.|[5]Gomaa SE, et al. The anti-staphylococcal fusidic acid as an efflux pump inhibitor combined with fluconazole against vaginal candidiasis in mouse model. BMC Microbiol. 2024 Feb 10;24 (1) :54.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
Launched
Citation 01
Cell Rep Med. 2023 Jun 20;4 (6) :101061.|Adv Sci (Weinh) . 2023 Sep;10 (25) :e2301753.|Cell Rep Med. 2023 Jun 20;4 (6) :101061.

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