ML372

CAT: 0013-GTR19197040-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19197040-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

ML372 is a potent and selective small molecule SMN2 splicing modulator, exhibiting an EC50 of 12 nM and increasing SMN protein levels by 325%. It demonstrates favorable pharmacokinetics, blood-brain barrier penetration, and tolerability, supporting its use in preclinical research for spinal muscular atrophy (SMA) in both cellular and animal models.

CAS Number

1331745-61-9

Field of Research

Cell Biology, Molecular Biology

Smiles

OC (=O) C1CCN (CC1) c1ncc (s1) -c1ccc2OCCCOc2c1

Molecular Formula

C18H20N2O4S

Molecular Weight

360.43

Storage Conditions

-20°C

Notes

For research use only.

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MBS5777764	ML372

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