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Ticolubant

CAT: 0013-GTR19196320-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19196320-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ticolubant is an orally bioavailable, potent antagonist of the leukotriene B4 (LTB4) receptor, exhibiting high binding affinity (Ki = 0.78 nM) and functional blockade of LTB4-induced calcium flux (IC50 = 6.6 nM) . It has demonstrated topical anti-inflammatory efficacy in murine models of skin inflammation, supporting its research use in studying LTB4-mediated pathways in neutrophil-driven inflammatory diseases.
CAS Number
154413-61-3
Product Name Alternative
CalciumChannel, Calcium Channel, LTB4, Ticolubant
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Purity
99.33% (May vary between batches)
Solubility
DMSO:50 mg/mL (108.61 mM)
Smiles
C (=C/C (O) =O) \C1=C (OCCC2=CC=CC=C2) C=CC (CSC3=C (Cl) C=CC=C3Cl) =N1
Molecular Formula
C23H19Cl2NO3S
Molecular Weight
460.37
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
M34447-01Ticolubant

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