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1-Methylpyrene

CAT: 0804-HY-W271064Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W271064Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
1-Methylpyrene is a ubiquitous environmental pollutant and rodent carcinogen. Its mutagenic activity depends on sequential activation by various CYP and sulfotransferase (SULT) enzymes. 1-Methylpyrene induces chromosome loss and mitotic disturbance, proba
CAS Number
2381-21-7
UNSPSC
12171500
Hazard Statement
H315, H319, H335
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/1-methylpyrene.html
Purity
99.51
Solubility
DMSO : 4.35 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1=C2C=CC3=CC=CC4=C3C2=C(C=C1)C=C4
Molecular Formula
C17H12
Molecular Weight
216.28
Precautions
H315, H319, H335
References & Citations
[1]Monien BH, et al. Time course of hepatic 1-methylpyrene DNA adducts in rats determined by isotope dilution LC-MS/MS and 32P-postlabeling. Chem Res Toxicol. 2008 Oct;21 (10) :2017-25. |[2]Hang Yu, et al. 1-Methylpyrene induces chromosome loss and mitotic apparatus damage in a Chinese hamster V79-derived cell line expressing both human CYP1A2 and sulfotransferase 1A1. Chem Biol Interact. 2020 Dec 1;332:109283.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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