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VU0410150

CAT: 0013-GTR19196174-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19196174-02Size:50 mg
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Description
VU0410150 is a pyrrylarylsulfone-based positive allosteric modulator of mGluR4, investigated as a potential therapeutic for Parkinson's disease. It has been utilized in both in vitro assays and in vivo animal models to study its neuroprotective and anti-parkinsonian effects, supporting its role in neurological research.
CAS Number
1296731-74-2
Smiles
S (=O) (=O) (N1C=C (NC (=O) C2=CC=CC=N2) C=C1) C3=CC (C) =C (C) C=C3
Molecular Formula
C18H17N3O3S
Molecular Weight
355.41
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-(1-((3,4-dimethylphenyl)sulfonyl)-1H-pyrrol-3-yl)picolinamide

a positive allosteric modulator of metabotropic glutamate receptor 4; structure in first source

CAS Number1296731-74-2
PubChem CID52914664
IUPAC NameN-[1-(3,4-dimethylphenyl)sulfonylpyrrol-3-yl]pyridine-2-carboxamide
Molecular FormulaC18H17N3O3S
Molecular Weight355.4
XLogP2.7
Topological Polar Surface Area89.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count25
Formal Charge0
Complexity575
SMILES
CC1=C(C=C(C=C1)S(=O)(=O)N2C=CC(=C2)NC(=O)C3=CC=CC=N3)C
InChI
InChI=1S/C18H17N3O3S/c1-13-6-7-16(11-14(13)2)25(23,24)21-10-8-15(12-21)20-18(22)17-5-3-4-9-19-17/h3-12H,1-2H3,(H,20,22)
InChIKey
LIVAPIWBIQYQLE-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(1-((3,4-dimethylphenyl)sulfonyl)-1H-pyrrol-3-yl)picolinamide
CAS: 1296731-74-2
CID: 52914664
Formula: C18H17N3O3S
MW: 355.4
Interactive 3D Structure
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View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight355.4
XLogP32.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass355.09906259
Monoisotopic Mass355.09906259
Topological Polar Surface Area89.4 Ų
Heavy Atom Count25
Formal Charge0
Complexity575
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
T29133-01VU0410150

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