MBP Ac1-9 (4Y)

MBP Ac1-9 (4Y)

• CAS Number: 167278-49-1
• UNSPSC Description: MBP Ac1-9 (4Y) is a synthetic peptide derived from a fragment of myelin basic protein (MBP) that has undergone specific chemical modifications. MBP Ac1-9 (4Y) is able to form a complex with the MHC class II molecule I-Au and activate specific T cell receptor (TCR), thus playing a role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE). MBP Ac1-9 (4Y) can be used to study autoimmune diseases, especially those involving the central nervous system, such as multiple sclerosis[1].
• Target Antigen: Others
• Type: Peptides
• Related Pathways: Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/mbp-ac1-9-4y.html
• Smiles: O=C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)NC(C)=O
• Molecular Weight: 1134.20
• References & Citations: [1]Huang J C, et al. T cell recognition of distinct peptide: I-Au conformers in murine experimental autoimmune encephalomyelitis[J]. The Journal of Immunology, 2003, 171(5): 2467-2477.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported