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Mouse Anti-Chicken CD8a-BIOT

CAT: 0544-MBS673976-01Size: 0.5 mgDry Ice: NoHazardous: No
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CAT#:0544-MBS673976-01Size:0.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
NCBI Gene ID
677754
Reactivity
Chicken
Storage Conditions
The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 °C.
The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze!
The Cyanine 5 (CY 5) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
Protect conjugated forms from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
Specificity
alpha chain of chicken CD8 (Mr 34 kDa)
In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two alpha chains, and (ii) a heterodimer of an alpha chain and a beta chain.1,2 Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells and 50% of spleen cells, but <1% of cells in the bursa and bone marrow.1 While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8 alpha - and CD8 beta -chains, a relatively large proportion of the CD8+ TCR- gamma delta cells in the spleens of embryos and young chicks express only the alpha -chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR- gamma delta CD8 alpha beta cells in the chicken that is not found in rodents.3 MAb 3-298 recognizes the CD8 alpha chain of both the chicken and turkey.4
Other Gene Names
[cd8a; cd8a; MGC136643; zgc:136643]
Short Name
[CD8 alpha]
Other Product Names
[CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide; CD8 alpha; CD8 antigen, alpha polypeptide]
NCBI GI Number
91176308
NCBI Accession Number
NP_001035138.1
NCBI GB Accession Number
NM_001040049.1
Uniprot Accession Number
Q24JW8

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