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Hamster Anti-Mouse CD81-BIOT

CAT: 0544-MBS673606-01Size: 0.5 mgDry Ice: NoHazardous: No
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CAT#:0544-MBS673606-01Size:0.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
NCBI Gene ID
975
Reactivity
Mouse
Storage Conditions
The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 °C.
The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze!
Protect conjugated forms from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 °C.
Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.
Specificity
Mouse CD81 (Mr 25 kDa), a member of the transmembrane 4 integral membrane protein family
CD81/TAPA-1 is an integral membrane protein expressed on a variety of cell types, and has a high degree of sequence homology between human and mouse.1 CD81 is expressed on thymic stromal cells where it plays an important role in the transition of gamma delta + T cells to more mature T cells with alpha beta T cell receptors.2 Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor, which is composed of a TCR beta chain and glycoprotein pT alpha.2 The monoclonal antibody 2F7 can block thymocyte interaction with CD81 in vitro.2
Other Gene Names
[CD81; CD81; S5.7; CVID6; TAPA1; TSPAN28; TAPA1; TSPAN28]
Short Name
[CD81/TAPA-1]
Other Product Names
[CD81 antigen; CD81 antigen; CD81 antigen; tspan-28; tetraspanin-28; OTTHUMP00000011528; OTTHUMP00000011529; OTTHUMP00000229004; OTTHUMP00000229005; OTTHUMP00000229006; OTTHUMP00000229008; OTTHUMP00000229358; OTTHUMP00000229392; 26 kDa cell surface protein TAPA-1; CD81 antigen (target of antiproliferative antibody 1); CD81 molecule; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; Tetraspanin-28]
NCBI GI Number
4757944
NCBI Accession Number
NP_004347.1
NCBI GB Accession Number
NM_004356.3
Uniprot Accession Number
P60033

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