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Hamster Anti-Mouse CD30-BIOT

CAT: 0544-MBS673315-01Size: 0.5 mgDry Ice: NoHazardous: No
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CAT#:0544-MBS673315-01Size:0.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
NCBI Gene ID
943
Reactivity
Mouse
Storage Conditions
The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 °C.
The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze!
The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 °C.
Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.
Specificity
Murine CD30, Mr 52 kDa (core peptide)
CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins.^1,2 Murine CD30 is expressed predominantly in the thymus, and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A.^1 In anti-CD3 epsilon -activated spleen cells, CD30 is expressed primarily on the surface of CD8^+ T cells with peak expression on days 4 and 5. Stimulation of CD30^+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN- gamma production. ^1 While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.
Other Gene Names
[TNFRSF8; TNFRSF8; CD30; Ki-1; D1S166E; CD30; D1S166E]
Short Name
[CD30]
Other Product Names
[CD30 antigen; Tumor necrosis factor receptor superfamily member 8; tumor necrosis factor receptor superfamily member 8; CD30 antigen; Ki-1 antigen; CD30L receptor; OTTHUMP00000001783; OTTHUMP00000221481; cytokine receptor CD30; lymphocyte activation antigen CD30; tumor necrosis factor receptor superfamily, member 8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30]
NCBI GI Number
180096
Uniprot Accession Number
P28908

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