Products for Research Use Only
RegisterLogin

Hamster Anti-Mouse CD3e-LE/AF

CAT: 0544-MBS673136-01Size: 0.5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0544-MBS673136-01Size:0.5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
NCBI Gene ID
654301
Reactivity
Mouse
Storage Conditions
The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 °C.
The fluorescein (FITC) and Cyanine 5 (CY 5) conjugates are supplied as 0.5 mg or 0.1 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
The R-phycoerythrin (R-PE), allophycocyanin (APC), and Spectral Red (SPRD) conjugates are supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze!
The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 °C.
The Alexa Fluor 647 (AF647) conjugate is supplies as 0.1 mg in 0.2mL of PBS/NaN3. Store at 2-8 °C.
Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.
Specificity
Mouse CD3 epsilon (Mr 25 kDa)
CD3 epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The 145-2C11 monoclonal antibody recognizes an epitope on the 25kD epsilon chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble 145-2C11 can activate primed and naïve T cell in vitro. 145-2C11 can also induce redirected lysis of specific target cells by CTL clones and it can block lysis of specific target cells by antigen-specific CTL's. Immobilized 145- 2C11 can activate both normal T lymphocytes and cloned T cell lines. Under certain conditions, T cell activation by 145-2C11 may result in apoptotic cell death. ^1-6
Other Gene Names
[cd3e]
Short Name
[CD3 epsilon]
Other Product Names
[CD3 epsilon; CD3 epsilon]
NCBI GI Number
83921647
NCBI Accession Number
NP_001033071.1
NCBI GB Accession Number
NM_001037982.1

Related Products

CatalogName
MBS673318-01Hamster Anti-Mouse CD30-LE/AF
MBS4151552-01Anti-Mouse CD3e-LE/AF Antibody
MBS4151560-01Anti-Mouse CD3e-LE/AF Antibody
MBS673153-01Rat Anti-Mouse CD3e-LE/AF
MBS673608-01Hamster Anti-Mouse CD81-LE/AF
MBS673304-01Hamster Anti-Mouse CD28-LE/AF
MBS673511-01Hamster Anti-Mouse TCRb-LE/AF
MBS673589-01Hamster Anti-Mouse CD103-LE/AF
MBS673312-01Hamster Anti-Mouse CD28-LE/AF
MBS673503-01Hamster Anti-Mouse TCRgd-LE/AF

Alternative Products

CatalogName
1715-14Hamster Anti-Mouse CD69-LE/AF
1615-14Hamster Anti-Mouse CD28-LE/AF
1790-14Hamster Anti-Mouse CD152-LE/AF
1531-14Hamster Anti-Mouse CD3ε-LE/AF
1810-14Hamster Anti-Mouse CD103-LE/AF
1807-14Hamster Anti-Mouse KLRG1-LE/AF
1785-14Hamster Anti-Mouse TCRβ-LE/AF
1620-14Hamster Anti-Mouse CD30-LE/AF
1825-14Hamster Anti-Mouse CD81-LE/AF
1830-14Hamster Anti-Mouse CD79b-LE/AF

Popular Products