Products for Research Use Only

S49076 HCl

CAT: 0013-GTR19192397-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19192397-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
S49076 HCl is a potent, orally active small molecule inhibitor targeting MET, AXL/MER, and FGFR1/2/3 kinases. It effectively blocks their phosphorylation and downstream signaling, inhibiting proliferation, migration, and colony formation in relevant cancer cell models. Demonstrated in vivo activity shows a strong pharmacokinetic/pharmacodynamic relationship correlating with antitumor efficacy in xenograft models.
CAS Number
1265966-31-1
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.17% (May vary between batches)
Smiles
Cl.O=C1CSC (=O) N1Cc1ccc2NC (=O) \C (=C/c3cc (CN4CCOCC4) c[nH]3) c2c1
Molecular Formula
C22H18ClN3O5
Molecular Weight
439.85
Storage Conditions
-20°C
Notes
For research use only.