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Cuspin-1

CAT: 0013-GTR19192016-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19192016-01Size:5 mg
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Description
Cuspin-1 is a small molecule that upregulates Survival of Motor Neuron (SMN) protein levels by activating the Ras-Raf-MEK-ERK pathway to enhance SMN translation. It has demonstrated efficacy in vitro, increasing SMN by 50% in SMA patient fibroblasts, and serves as a valuable research tool for studying SMA mechanisms and therapeutic strategies.
CAS Number
337932-29-3
Field of Research
Signal Transduction
Smiles
Cc1ccc (cc1) C (=O) c1cncc (Br) c1
Molecular Formula
C13H10BrNO
Molecular Weight
276.13
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

3-Bromo-5-(4-methylbenzoyl)pyridine
CAS Number337932-29-3
PubChem CID2055944
IUPAC Name(5-bromo-3-pyridinyl)-(4-methylphenyl)methanone
Molecular FormulaC13H10BrNO
Molecular Weight276.13
XLogP3.3
Topological Polar Surface Area30
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Heavy Atom Count16
Formal Charge0
Complexity248
SMILES
CC1=CC=C(C=C1)C(=O)C2=CC(=CN=C2)Br
InChI
InChI=1S/C13H10BrNO/c1-9-2-4-10(5-3-9)13(16)11-6-12(14)8-15-7-11/h2-8H,1H3
InChIKey
AJZRSLVRFSCCIL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-Bromo-5-(4-methylbenzoyl)pyridine
CAS: 337932-29-3
CID: 2055944
Formula: C13H10BrNO
MW: 276.13
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight276.13
XLogP33.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass274.99458
Monoisotopic Mass274.99458
Topological Polar Surface Area30 Ų
Heavy Atom Count16
Formal Charge0
Complexity248
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
MNA93229-01Cuspin 1
HY-119460-01Cuspin-1
217293Cuspin-1 ((5-Bromo-3-pyridinyl) (4-methylphenyl) methanone, Survival Motor Neuron Protein Upregulator, Cuspin-1) discontinued
OF59775-011,1,1,1,1-Kestoheptaose
N2864-5.11,1,1,1-Kestohexaose
1120401,1,1,1-Kestohexose
410417-011,1,1-Trichloromethanesulfonic Acid 1,1'-Anhydride
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