Products for Research Use Only
RegisterLogin

SR 1903

CAT: 0013-GTR19191982-02Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19191982-02Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SR 1903 is a dual modulator acting as an inverse agonist of RORγ and an agonist of LXR, with additional binding to PPARγ. It suppresses pro-inflammatory pathways in vitro and demonstrates efficacy in mouse models of arthritis and obesity by improving metabolic parameters and reducing disease severity.
CAS Number
1414248-06-8
Field of Research
Metabolism Research, Molecular Biology
Purity
99.93% (May vary between batches)
Smiles
FC (F) (F) C (O) (C1=CC=C (C=C1) C=2C=CC (=CC2C) CN3CCN (CC=4C=CN=CC4) CC3) C (F) (F) F
Molecular Formula
C27H27F6N3O
Molecular Weight
523.51
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1,1,1,3,3,3-Hexafluoro-2-[4-[2-methyl-4-[[4-(pyridin-4-ylmethyl)piperazin-1-yl]methyl]phenyl]phenyl]propan-2-ol
CAS Number1414248-06-8
PubChem CID71470724
IUPAC Name1,1,1,3,3,3-hexafluoro-2-[4-[2-methyl-4-[[4-(pyridin-4-ylmethyl)piperazin-1-yl]methyl]phenyl]phenyl]propan-2-ol
Molecular FormulaC27H27F6N3O
Molecular Weight523.5
XLogP5.2
Topological Polar Surface Area39.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count10
Rotatable Bond Count6
Heavy Atom Count37
Formal Charge0
Complexity696
SMILES
CC1=C(C=CC(=C1)CN2CCN(CC2)CC3=CC=NC=C3)C4=CC=C(C=C4)C(C(F)(F)F)(C(F)(F)F)O
InChI
InChI=1S/C27H27F6N3O/c1-19-16-21(18-36-14-12-35(13-15-36)17-20-8-10-34-11-9-20)2-7-24(19)22-3-5-23(6-4-22)25(37,26(28,29)30)27(31,32)33/h2-11,16,37H,12-15,17-18H2,1H3
InChIKey
HSUQYJQLSYQEOB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1,1,1,3,3,3-Hexafluoro-2-[4-[2-methyl-4-[[4-(pyridin-4-ylmethyl)piperazin-1-yl]methyl]phenyl]phenyl]propan-2-ol
CAS: 1414248-06-8
CID: 71470724
Formula: C27H27F6N3O
MW: 523.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight523.5
XLogP35.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count10
Rotatable Bond Count6
Exact Mass523.20583147
Monoisotopic Mass523.20583147
Topological Polar Surface Area39.6 Ų
Heavy Atom Count37
Formal Charge0
Complexity696
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19201133-01MK 1903
GTR19244171-01MK 1903
GTR19313592-01Mmu-miR-1903 miRNA Agomir
GTR19313589-01Mmu-miR-1903 miRNA Inhibitor
GTR19313588-01Mmu-miR-1903 miRNA Mimic
GTR19313590-01Mmu-miR-1903 miRNA Antagomir
GTR19208984-01SR 27417A
GTR19208982-01SR 27388
GTR19200808SR 140333
GTR19200805-01SR 16584

Alternative Products

CatalogName
T22986-01MK 1903
MBS5796957SR 1903
VHA51463-01AP 1903
HY-138007-01SR-1903
MBS130273-01AP-1903
6766/25AC 1903
HY-107581-01MK-1903
HY-RI02728A-01Mmu-miR-1903 antagomir
HY-R02728A-01Mmu-miR-1903 agomir
HY-R02728-01Mmu-miR-1903 mimic

Popular Products