Products for Research Use Only

Simotinib

CAT: 0013-GTR19191747Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19191747Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Simotinib (AL-6802) is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 19.9 nM. It demonstrates anti-tumor activity in non-small cell lung cancer (NSCLC) research, showing efficacy in both in vitro cellular assays and in vivo xenograft models.
CAS Number
944258-89-3
Product Name Alternative
Simotinib, SIM-6802, AL-6802, EGFR
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.70% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2 mM) ; DMSO:10 mg/mL (19.96 mM)
Smiles
COc1cc2ncnc (Nc3ccc (F) c (Cl) c3) c2cc1OCCN1CC2 (CC2) C2 (C1) OCCO2
Molecular Formula
C25H26ClFN4O4
Molecular Weight
500.95
Storage Conditions
-20°C
Notes
For research use only.

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