Products for Research Use Only
RegisterLogin

AZD 3147

CAT: 0013-GTR19192046-03Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19192046-03Size:1 ml x 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
AZD 3147 is a potent and selective mTORC inhibitor, demonstrating IC50 values of 5.75 nM for mTORC2 and 40.7 nM for mTORC1, with significantly lower activity against PI3K isoforms. This selectivity profile makes it a valuable chemical probe for studying mTOR signaling in cancer research and cellular biology, applicable in both in vitro and in vivo experimental models.
CAS Number
1101810-02-9
Product Name Alternative
AZD3147, AZD-3147, AZD 3147, mTORC1, mTORC2
Field of Research
Signal Transduction
Purity
98.34% (May vary between batches)
Solubility
Hydrochloride acid:100 mg/mL (193.18 mM) ; Ethanol:1 mg/mL (1.93 mM) ; DMSO:46.8 mg/mL (90.41 mM)
Smiles
S (=O) (=O) (C1 (CC1) C=2C=C (N=C (N2) C3=CC=C (NC (NCCO) =S) C=C3) N4[C@@H] (C) COCC4) C5CC5
Molecular Formula
C24H31N5O4S2
Molecular Weight
517.66
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1-[4-[4-(1-cyclopropylsulfonylcyclopropyl)-6-[(3S)-3-methylmorpholin-4-yl]pyrimidin-2-yl]phenyl]-3-(2-hydroxyethyl)thiourea
CAS Number1101810-02-9
PubChem CID25168990
IUPAC Name1-[4-[4-(1-cyclopropylsulfonylcyclopropyl)-6-[(3S)-3-methylmorpholin-4-yl]pyrimidin-2-yl]phenyl]-3-(2-hydroxyethyl)thiourea
Molecular FormulaC24H31N5O4S2
Molecular Weight517.7
XLogP1.4
Topological Polar Surface Area157
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Heavy Atom Count35
Formal Charge0
Complexity852
SMILES
C[C@H]1COCCN1C2=NC(=NC(=C2)C3(CC3)S(=O)(=O)C4CC4)C5=CC=C(C=C5)NC(=S)NCCO
InChI
InChI=1S/C24H31N5O4S2/c1-16-15-33-13-11-29(16)21-14-20(24(8-9-24)35(31,32)19-6-7-19)27-22(28-21)17-2-4-18(5-3-17)26-23(34)25-10-12-30/h2-5,14,16,19,30H,6-13,15H2,1H3,(H2,25,26,34)/t16-/m0/s1
InChIKey
JWGVUDPAMQEIJU-INIZCTEOSA-N
Chemical Structure
2D Structure
2D structure of 1-[4-[4-(1-cyclopropylsulfonylcyclopropyl)-6-[(3S)-3-methylmorpholin-4-yl]pyrimidin-2-yl]phenyl]-3-(2-hydroxyethyl)thiourea
CAS: 1101810-02-9
CID: 25168990
Formula: C24H31N5O4S2
MW: 517.7
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight517.7
XLogP31.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Exact Mass517.18174683
Monoisotopic Mass517.18174683
Topological Polar Surface Area157 Ų
Heavy Atom Count35
Formal Charge0
Complexity852
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19211596-01AZD-1386
GTR19208998-01AZD-4121
GTR19206525AZD 2066
GTR19206524-01AZD-8529
GTR19206522-01AZD-5991
GTR19195502-01AZD 7009
GTR19195499-01AZD-1305
GTR19195494-01AZD-3161
GTR19175193-01AZD-0284
GTR19171537-01AZD-5672

Alternative Products

CatalogName
BUP02471-01AZD 3147
MPH01362hsa-miR-3147 Primers
HY-R00591-01Hsa-miR-3147 mimic
HY-RI00591-01Hsa-miR-3147 inhibitor
HY-R00591A-01Hsa-miR-3147 agomir
HY-RI00591A-01Hsa-miR-3147 antagomir
CMH0934-01Hsa-miR-3147 miRNA Mimic
MBS8316876-01hsa-miR-3147 miRNA Antagomir
MBS8311629-01hsa-miR-3147 miRNA Agomir
CIH0934-01Hsa-miR-3147 miRNA Inhibitor

Popular Products