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CCR2 antagonist 5

CAT: 0013-GTR19197405-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19197405-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JNJ-41443532 is a potent, selective, and orally bioavailable antagonist of human CCR2 (IC50=37 nM) with demonstrated efficacy in inhibiting monocyte chemotaxis. Its significant species selectivity makes it a valuable pharmacological tool for studying CCR2-mediated pathways in preclinical models of inflammation and metabolic disorders like diabetes.
CAS Number
1228650-83-6
Product Name Alternative
JNJ41443532, JNJ-41443532, JNJ-41443532 Free Base, JNJ 41443532, CCR2, CCR2 antagonist 5
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
98.79% (May vary between batches)
Solubility
DMSO:50 mg/mL (103.62 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (5.18 mM)
Smiles
N (C (CNC (=O) C1=CC (C (F) (F) F) =CC=C1) =O) C2CN ([C@@H]3CC[C@@] (O) (CC3) C4=CN=CS4) C2
Molecular Formula
C22H25F3N4O3S
Molecular Weight
482.52
Storage Conditions
-20°C
Notes
For research use only.

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