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HG-7-85-01

CAT: 0013-GTR19189778-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19189778-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HG-7-85-01 is a potent ATP-competitive, type II inhibitor targeting BCR-ABL (including T315I mutant), PDGFRα, Kit, and Src kinases. It demonstrates robust anti-proliferative activity in vitro, inducing cell cycle arrest and apoptosis in leukemia cell lines, and has shown efficacy in preclinical in vivo models of BCR-ABL-driven cancers.
CAS Number
1258391-13-7
Product Name Alternative
HG78501, HG-7-85-01, HG 7 85 01
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.08% (May vary between batches)
Solubility
DMSO:100 mg/mL (164.29 mM)
Smiles
O=C (NC1=CC=C (C (=C1) C (F) (F) F) CN2CCN (CC) CC2) C3=CC=CC (=C3) C4=NC=5SC (=NC5C=C4) NC (=O) C6CC6
Molecular Formula
C31H31F3N6O2S
Molecular Weight
608.68
Storage Conditions
-20°C
Notes
For research use only.

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