Products for Research Use Only

NS-102

CAT: 0013-GTR19189709-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19189709-02Size:5 mg
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Description
NS-102 is a selective antagonist of the GluK2-containing kainate receptor (formerly known as GLUR6) . It functions by inhibiting specific binding and receptor-mediated currents, making it a valuable research tool for studying kainate receptor roles in synaptic transmission, plasticity, and neurological disease models in vitro and in vivo.
CAS Number
136623-01-3
Product Name Alternative
NS 102, NS102, NS-102, NMDA receptor, GluR
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
97.96% (May vary between batches)
Solubility
DMSO:2 mg/mL (7.66 mM)
Smiles
O\N=C1/C (=O) Nc2c1cc (c1CCCCc21) [N+] ([O-]) =O
Molecular Formula
C12H11N3O4
Molecular Weight
261.23
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

5-Nitro-6,7,8,9-tetrahydrobenzo(G)indole-2,3-dione-3-oxime

NS-102 is a nitronaphthalene.

CAS Number136623-01-3
PubChem CID4461601
IUPAC Name5-nitro-3-nitroso-6,7,8,9-tetrahydro-1H-benzo[g]indol-2-ol
Molecular FormulaC12H11N3O4
Molecular Weight261.23
XLogP3.2
Topological Polar Surface Area111
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Heavy Atom Count19
Formal Charge0
Complexity386
SMILES
C1CCC2=C3C(=CC(=C2C1)[N+](=O)[O-])C(=C(N3)O)N=O
InChI
InChI=1S/C12H11N3O4/c16-12-11(14-17)8-5-9(15(18)19)6-3-1-2-4-7(6)10(8)13-12/h5,13,16H,1-4H2
InChIKey
SADZJARZJNQZHT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 5-Nitro-6,7,8,9-tetrahydrobenzo(G)indole-2,3-dione-3-oxime
CAS: 136623-01-3
CID: 4461601
Formula: C12H11N3O4
MW: 261.23
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight261.23
XLogP33.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Exact Mass261.07495584
Monoisotopic Mass261.07495584
Topological Polar Surface Area111 Ų
Heavy Atom Count19
Formal Charge0
Complexity386
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes