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Thailanstatin D

CAT: 0013-GTR19189565Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19189565Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thailanstatin D is a potent small molecule that disrupts the U2AF65-SAP155 interaction, inhibiting AR-V7 splicing. This mechanism leads to significant antitumor activity and apoptosis in castration-resistant prostate cancer models, as demonstrated in both in vitro studies and in vivo xenograft experiments.
CAS Number
1609105-89-6
Field of Research
Cell Biology, Molecular Biology
Smiles
C[C@H] (OC (C) =O) \C=C/C (=O) N[C@@H]1C[C@H] (C) [C@H] (C\C=C (/C) \C=C\[C@@H]2C[C@]3 (CO3) C[C@@H] (CC (O) =O) O2) O[C@@H]1C
Molecular Formula
C28H41NO8
Molecular Weight
519.635
Storage Conditions
-20°C
Notes
For research use only.

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