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PROTAC ERRα Degrader-3

CAT: 0013-GTR19189236-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19189236-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC ERRα Degrader-3 is a potent and selective VHL-based degrader of ERRα, achieving >80% degradation at 30 nM with no off-target activity against ERRβ/γ. This tool compound is valuable for investigating ERRα's role in cancer, metabolism, and bone biology in both cellular and in vivo models.
CAS Number
2306388-65-6
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
COc1cc (\C=C (/C#N) C (=O) NCCCCC (=O) N[C@H] (C (=O) N2C[C@H] (O) C[C@H]2C (=O) NCc2ccc (cc2) -c2scnc2C) C (C) (C) C) ccc1OCc1ccc (cc1C (F) (F) F) C (F) (F) F
Molecular Formula
C47H50F6N6O7S
Molecular Weight
957.0
Storage Conditions
-20°C
Notes
For research use only.

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HY-139185-01PROTAC ERRα Degrader-3
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