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FNC-TP

CAT: 0013-GTR19189060Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19189060Size:1 mg
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Description
FNC-TP is the intracellularly active metabolite of FNC, functioning as a broad-spectrum nucleoside reverse transcriptase inhibitor. It demonstrates antiviral activity against HIV, HBV, and HCV in biochemical and cellular assays, supporting its investigation in antiviral research.
CAS Number
2457357-99-0
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Smiles
Nc1ccn ([C@@H]2O[C@@] (COP (O) (=O) OP (O) (=O) OP (O) (O) =O) (N=[N+]=[N-]) [C@@H] (O) [C@@H]2F) c (=O) n1
Molecular Formula
C9H14FN6O13P3
Molecular Weight
526.16
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Fnc-TP
CAS Number2457357-99-0
PubChem CID49771639
IUPAC Name[[(2R,3R,4S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-2-azido-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Molecular FormulaC9H14FN6O13P3
Molecular Weight526.16
XLogP-4.6
Topological Polar Surface Area262
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count16
Rotatable Bond Count9
Heavy Atom Count32
Formal Charge0
Complexity1030
SMILES
C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@](O2)(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)N=[N+]=[N-])O)F
InChI
InChI=1S/C9H14FN6O13P3/c10-5-6(17)9(14-15-12,27-7(5)16-2-1-4(11)13-8(16)18)3-26-31(22,23)29-32(24,25)28-30(19,20)21/h1-2,5-7,17H,3H2,(H,22,23)(H,24,25)(H2,11,13,18)(H2,19,20,21)/t5-,6-,7+,9+/m0/s1
InChIKey
BRACSMALKQTJNX-XZMZPDFPSA-N
Chemical Structure
2D Structure
2D structure of Fnc-TP
CAS: 2457357-99-0
CID: 49771639
Formula: C9H14FN6O13P3
MW: 526.16
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight526.16
XLogP3-4.6
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count16
Rotatable Bond Count9
Exact Mass525.98157368
Monoisotopic Mass525.98157368
Topological Polar Surface Area262 Ų
Heavy Atom Count32
Formal Charge0
Complexity1030
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count1
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes