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Sinbaglustat

CAT: 0013-GTR19189004-08Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19189004-08Size:200 mg
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Description
Sinbaglustat (OGT2378) is an orally bioavailable, brain-penetrant N-alkyl iminosugar functioning as a dual inhibitor of glucosylceramide synthase (GCS) and non-lysosomal glucosylceramidase (GBA2) . It is a research tool for investigating lysosomal storage disorders like Gaucher disease and related neurodegenerative pathologies in both cellular and animal models.
CAS Number
441061-33-2
Product Name Alternative
Glucosylceramide synthase, OGT 2378, OGT2378, OGT-2378, ACT519276, ACT-519276, ACT 519276, Sinbaglustat
Field of Research
Metabolism Research
Purity
99.93% (May vary between batches)
Solubility
DMSO:46.66 mg/mL (200 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (21.43 mM)
Smiles
CCCCCN1C[C@H] (O) [C@@H] (O) [C@H] (O) [C@@H]1CO
Molecular Formula
C11H23NO4
Molecular Weight
233.3
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Sinbaglustat

an antineopl agent; structure in first source

CAS Number441061-33-2
PubChem CID9859470
IUPAC Name(2S,3R,4R,5S)-2-(hydroxymethyl)-1-pentylpiperidine-3,4,5-triol
Molecular FormulaC11H23NO4
Molecular Weight233.30
XLogP-0.1
Topological Polar Surface Area84.2
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count16
Formal Charge0
Complexity202
SMILES
CCCCCN1C[C@@H]([C@H]([C@@H]([C@@H]1CO)O)O)O
InChI
InChI=1S/C11H23NO4/c1-2-3-4-5-12-6-9(14)11(16)10(15)8(12)7-13/h8-11,13-16H,2-7H2,1H3/t8-,9-,10+,11+/m0/s1
InChIKey
HCZQIIVHWYFIPW-UKKRHICBSA-N
Chemical Structure
2D Structure
2D structure of Sinbaglustat
CAS: 441061-33-2
CID: 9859470
Formula: C11H23NO4
MW: 233.30
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight233.30
XLogP3-0.1
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass233.16270821
Monoisotopic Mass233.16270821
Topological Polar Surface Area84.2 Ų
Heavy Atom Count16
Formal Charge0
Complexity202
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA8493-5.1Sinbaglustat

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