Products for Research Use Only
RegisterLogin

MLKL-IN-2

CAT: 0013-GTR19188697-02Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19188697-02Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MLKL-IN-2 is a small molecule inhibitor targeting mixed lineage kinase domain-like protein (MLKL) to suppress necroptosis. It is a valuable research tool for investigating necroptosis-related pathologies, including inflammatory and neurodegenerative diseases, in both cellular and animal models.
CAS Number
899759-16-1
Product Name Alternative
MLKL, MLKL IN 2, MLKLIN2, MLKL-IN-2
Field of Research
Signal Transduction
Purity
98.30% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.36 mM) ; DMSO:4.24 mg/mL (10.01 mM)
Smiles
CN1CCN (CC1) c1ccc (nn1) -c1cccc (NC (=O) c2ccc3ccccc3c2) c1
Molecular Formula
C26H25N5O
Molecular Weight
423.51
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Mlkl-IN-2
CAS Number899759-16-1
PubChem CID7593182
IUPAC NameN-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]naphthalene-2-carboxamide
Molecular FormulaC26H25N5O
Molecular Weight423.5
XLogP3.9
Topological Polar Surface Area61.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Heavy Atom Count32
Formal Charge0
Complexity621
SMILES
CN1CCN(CC1)C2=NN=C(C=C2)C3=CC(=CC=C3)NC(=O)C4=CC5=CC=CC=C5C=C4
InChI
InChI=1S/C26H25N5O/c1-30-13-15-31(16-14-30)25-12-11-24(28-29-25)21-7-4-8-23(18-21)27-26(32)22-10-9-19-5-2-3-6-20(19)17-22/h2-12,17-18H,13-16H2,1H3,(H,27,32)
InChIKey
CVHOXUUPSXOTPM-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Mlkl-IN-2
CAS: 899759-16-1
CID: 7593182
Formula: C26H25N5O
MW: 423.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight423.5
XLogP33.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass423.20591044
Monoisotopic Mass423.20591044
Topological Polar Surface Area61.4 Ų
Heavy Atom Count32
Formal Charge0
Complexity621
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR17695953Phospho-MLKL/MLKL Rabbit Monoclonal Antibody
GTR19212253-01MLKL-IN-5
GTR19187572-01MLKL-IN-1
GTR18591123-01MLKL Antibody
GTR18591122-01MLKL Antibody
GTR19262033-01MLKL-IN-7
GTR19230311-01MLKL-IN-6
GTR18188822-01MLKL Antibody
GTR18132594MLKL Antibody
GTR18781994-01MLKL Antibody

Alternative Products

CatalogName
HY-141889-01MLKL-IN-2
T200218-01PROTAC MLKL Degrader-2
MBS8563429-01MLKL
TMAB-08853-01Anti-MLKL Polyclonal Antibody 2
T209391-01MLKL-IN-7
T60885-01MLKL-IN-1
GWB-MS902BMLKL Antibody
AF6903-BPMLKL Peptide

Popular Products