Anti - PUMA, alpha (p53 Upregulated Modulator of Apoptosis)

• NCBI Gene ID:

  27113

• Reactivity:

  Human

• Storage Conditions:

  May be stored at 4 °C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 °C. Aliquots are stable for at least 12 months at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

• Specificity:

  Human control peptide sequence is also found in alternatively spliced PUMA-beta but not in gamma or delta forms. 88% conserved in mouse PUMA-alpha. No significant sequence homology is detected with other proteins. Control peptide, because of its low MW (<3kD), is not suitable for Western. It should be used for ELISA or antibody blocking experiments (use 5-10 ug control peptide per 1 ug of aff pure IgG or 1 ul antiserum) to confirm antibody specificity.

• Other Gene Names:

  [BBC3; BBC3; JFY1; PUMA; FLJ42994; PUMA]

• Short Name:

  [PUMA, alpha]

• Other Product Names:

  [PUMA alpha; Bcl-2-binding component 3; bcl-2-binding component 3; JFY-1; p53 up-regulated modulator of apoptosis; BCL2 binding component 3; JFY-1; p53 up-regulated modulator of apoptosis]

• NCBI GI Number:

  13785988

• Uniprot Accession Number:

  Q9BXH1

• CAS Number:

  9007-83-4