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MK-5108

CAT: 0013-GTR19187787-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19187787-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MK-5108 (VX-689) is a highly selective, sub-nanomolar inhibitor of Aurora-A kinase (IC50 = 0.064 nM) . It is widely used in cancer research to study mitotic progression and has demonstrated antitumor activity in both cellular assays and in vivo xenograft models.
CAS Number
1010085-13-8
Product Name Alternative
Inhibit, MK 5108, MK5108, MK-5108, Inhibitor, Autophagy, AuroraKinase, Aurora A, Aurora Kinase, VX 689, VX689, VX-689
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
98.76% (May vary between batches)
Solubility
DMSO:50 mg/mL (108.24 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.33 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
OC (=O) [C@@]1 (Cc2cccc (Nc3nccs3) n2) CC[C@@H] (CC1) Oc1cccc (Cl) c1F
Molecular Formula
C22H21ClFN3O3S
Molecular Weight
461.94
Storage Conditions
-20°C
Notes
For research use only.

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