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EM127

CAT: 0013-GTR19187686-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19187686-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EM127 is a potent, selective covalent inhibitor of SMYD3 (KD = 13 μM) that suppresses its methyltransferase activity, ERK1/2 phosphorylation, and target gene transcription. This compound is a valuable research tool for investigating SMYD3-positive cancers in both cellular and animal models.
CAS Number
1886879-71-5
Product Name Alternative
SMYD3, ERK2, ERK1, Histone Methyltransferase, HistoneMethyltransferase
Field of Research
Epigenetics & Chromatin, Signal Transduction
Purity
97.55% (May vary between batches)
Solubility
DMSO:20 mg/mL (64.15 mM)
Smiles
ClCC (=O) N1CCC (CC1) NC (=O) c1cc (on1) C1CC1
Molecular Formula
C14H18ClN3O3
Molecular Weight
311.76
Storage Conditions
-20°C
Notes
For research use only.

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