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HFI-419

CAT: 0013-GTR19187298-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19187298-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HFI-419 is a potent and selective inhibitor of insulin-regulated aminopeptidase (IRAP) with a K i of 0.48 μM. This small molecule is a valuable research tool for studying cognitive function in models of Alzheimer's disease, stroke, and traumatic brain injury, based on its role in modulating memory-related neuropeptides in both in vitro and in vivo experiments.
CAS Number
1110650-72-0
Smiles
C (OCC) (=O) C=1C (C=2C (OC1NC (C) =O) =CC (O) =CC2) C=3C=CC=NC3
Molecular Formula
C19H18N2O5
Molecular Weight
354.36
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

ethyl 2-acetamido-7-hydroxy-4-(pyridin-3-yl)-4H-chromene-3-carboxylate
CAS Number1110650-72-0
PubChem CID42601512
IUPAC Nameethyl 2-acetamido-7-hydroxy-4-pyridin-3-yl-4H-chromene-3-carboxylate
Molecular FormulaC19H18N2O5
Molecular Weight354.4
XLogP2.2
Topological Polar Surface Area97.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Heavy Atom Count26
Formal Charge0
Complexity576
SMILES
CCOC(=O)C1=C(OC2=C(C1C3=CN=CC=C3)C=CC(=C2)O)NC(=O)C
InChI
InChI=1S/C19H18N2O5/c1-3-25-19(24)17-16(12-5-4-8-20-10-12)14-7-6-13(23)9-15(14)26-18(17)21-11(2)22/h4-10,16,23H,3H2,1-2H3,(H,21,22)
InChIKey
GGBHINRNYAAYMX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of ethyl 2-acetamido-7-hydroxy-4-(pyridin-3-yl)-4H-chromene-3-carboxylate
CAS: 1110650-72-0
CID: 42601512
Formula: C19H18N2O5
MW: 354.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight354.4
XLogP32.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass354.12157168
Monoisotopic Mass354.12157168
Topological Polar Surface Area97.8 Ų
Heavy Atom Count26
Formal Charge0
Complexity576
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
T61258-01HFI-419
HNA16434-01HFI-142
HY-160239-01HFI-437
A19709-100HFI-142 100mg
A19709-10HFI-142 10mg
A19709-50HFI-142 50mg
A19709-5HFI-142 5mg
A19709-2HFI-142 2mg
A19709-25HFI-142 25mg
HY-111314-01NZ 419

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