Products for Research Use Only

ATR-IN-15

CAT: 0013-GTR19186949-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19186949-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ATR-IN-15 (compound 1) is a potent, orally bioavailable ATR kinase inhibitor (IC50 = 8 nM) with additional activity against DNA-PK and PI3K. It demonstrates efficacy in cellular models, such as LoVo colon tumor cells, making it a valuable chemical probe for studying DNA damage response pathways in cancer research.
CAS Number
2756665-52-6
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
CC=1N2C (=C (N1) C=3C=CNN3) N=C (C=C2N4[C@H] (C) COCC4) C=5N (C) N=CC5
Molecular Formula
C19H22N8O
Molecular Weight
378.43
Storage Conditions
-20°C
Notes
For research use only.