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PKC-IN-4

CAT: 0013-GTR19186930-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19186930-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PKC-IN-4 (compound 7l) is a potent, orally bioavailable inhibitor of atypical PKC (IC50 = 0.52 μM) . It suppresses TNF-α-induced NF-κB activity in vitro and reduces VEGF/TNFα-mediated retinal vascular permeability, supporting research in oncology, inflammation, and diabetic retinopathy.
CAS Number
2636771-29-2
Field of Research
Epigenetics & Chromatin, Signal Transduction
Smiles
C (N) C1CCN (C2=C3C (SC4=C3CCCC4) =NC (=N2) C=5C=CN=CC5) CC1
Molecular Formula
C21H25N5S
Molecular Weight
379.52
Storage Conditions
-20°C
Notes
For research use only.

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