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CDK8-IN-11

CAT: 0013-GTR19186784-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19186784-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK8-IN-11 is a selective and potent CDK8 inhibitor with antiproliferative effects in colon cancer models. It suppresses WNT/β-catenin signaling and TCF transcriptional activity, inducing G1-phase arrest in vitro, such as in HCT-116 cells, making it a useful tool for oncology and signaling pathway research.
CAS Number
2839338-28-0
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.74% (May vary between batches)
Solubility
DMSO:200 mg/mL (515.01 mM)
Smiles
O=C (NC1=CC=C (OC2=CN=C (N) C=C2) C=C1) NC3=CC=CC (=C3) C (F) (F) F
Molecular Formula
C19H15F3N4O2
Molecular Weight
388.34
Storage Conditions
-20°C
Notes
For research use only.

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