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BACE1/2-IN-1

CAT: 0013-GTR19186560-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19186560-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BACE1/2-IN-1 (compound 34) is a potent dual inhibitor of BACE1 and BACE2 enzymes, exhibiting IC50 values of 0.01 and 0.0053 μM, respectively. It features a favorable pharmacokinetic profile with reduced Pgp efflux and enhanced permeability, though it shows decreased metabolic stability in liver microsomes. This inhibitor is a valuable research tool for in vitro and in vivo studies investigating Alzheimer's disease and type 2 diabetes.
CAS Number
2671036-34-1
Field of Research
Cell Biology, Neuroscience
Smiles
C (OC[C@H]1[C@H] (C) C1) (C) (C) [C@H]2[C@] ([C@@]34[C@@] (CN (C3) C=5N=CC=CN5) (CSC (N) =N4) [H]) (C2) [H]
Molecular Formula
C21H31N5OS
Molecular Weight
401.57
Storage Conditions
-20°C
Notes
For research use only.

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