2-NBDG

CAT: 0804-HY-116215-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-116215-01Size:1 mg
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Description
2-NBDG is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.
CAS Number
[186689-07-6]
Product Name Alternative
NVP-AEE 788
UNSPSC
12171500
Hazard Statement
H315, H319, H335
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-NBDG.html
Purity
99.74
Solubility
H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C[C@H](NC1=CC=C([N+]([O-])=O)C2=NON=C21)[C@H]([C@@H]([C@@H](CO)O)O)O
Molecular Formula
C12H14N4O8
Molecular Weight
342.26
Precautions
H315, H319, H335
References & Citations
[1]Zou C, et al. 2-NBDG as a fluorescent indicator for direct glucose uptake measurement. J Biochem Biophys Methods. 2005 Sep 30;64 (3) :207-15.|[2]Katsuya Yamada, et al. A real-time method of imaging glucose uptake in single, living mammalian cells. Nat Protoc. 2007;2 (3) :753-62.|[3]Yamada K, et al. A real-time method of imaging glucose uptake in single, living mammalian cells. Nat Protoc. 2007;2 (3) :753-62.|[4]Zou C, et al. 2-NBDG as a fluorescent indicator for direct glucose uptake measurement. J Biochem Biophys Methods. 2005 Sep 30;64 (3) :207-15.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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