Fluorescein

• Description:

  Fluorescein (Uranine) is widely used as a fluorescent tracer in medicinal and biological applications and tumor infected tissues tracer. Fluorescein (Uranine) is a representative green fluorophore that has been widely used as a scaffold of practically useful green fluorescent probes[1][2].

• Product Name Alternative:

  Uranine

• UNSPSC:

  12171500

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Fluorescein.html

• Purity:

  98.47

• Solubility:

  DMSO : 83.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

• Smiles:

  O=C1OC2(C3=C(OC4=C2C=CC(O)=C4)C=C(O)C=C3)C5=C1C=CC=C5

• Molecular Formula:

  C20H12O5

• Molecular Weight:

  332.31

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]RobertSjöback, et al. Absorption and fluorescence properties of fluorescein. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy|[2]Nabel A Negm, et al. Fluorescein dye derivatives and their nanohybrids: Synthesis, characterization and antimicrobial activity. J Photochem Photobiol B. 2016 Sep;162:421-433.|[3]Li Liu, et al. Fluorescein as an artificial enzyme to mimic peroxidase. Chem Commun (Camb) . 2016 Nov24;52 (96) :13912-13915.|[4]Hirabayashi K, et al. Analysis of chemical equilibrium of silicon-substituted fluorescein and its application to develop a scaffold for red fluorescent probes. Anal Chem. 2015;87 (17) :9061-9069.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  RT, protect from light, stored under nitrogen

• Scientific Category:

  Dye Reagents

• Clinical Information:

  Launched

• Citation 01:

  Brain Res. 2024 Jul 15:1835:148919.|Cell Death Dis. 2023 Feb 7;14 (2) :91.|Commun Biol. 2025 Apr 26;8 (1) :667.|Dev Dyn. 2025 Jun;254 (6) :513-537.|J Otol. 2025 Nov 13;20 (4) :211-218.|Med Mol Morphol. 2025 Nov 10.|Brain Res Bull. 2025 Sep:229:111479.|Gene. 2025 Jan 27:149292.|J Agric Food Chem. 2025 Jul 16;73 (28) :17696-17712.|J Neurosurg. 2018 Sep 7;131 (3) :724-734.|Sci Bull. 2024 Mar 15;69 (5) :621-635.

• CAS Number:

  [2321-07-5]