Products for Research Use Only
RegisterLogin

Cap-dependent endonuclease-IN-17

CAT: 0013-GTR19184628-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19184628-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cap-dependent endonuclease-IN-17 is a potent inhibitor of the influenza virus cap-dependent endonuclease (CEN) . It demonstrates antiviral activity with an IC50 of 1.29 μM against the influenza A/H3N2 strain. This compound is a valuable research tool for studying influenza virus replication mechanisms in vitro.
CAS Number
2649362-71-8
Field of Research
Infectious Disease & Virology
Smiles
O (P (=O) (O) O) C1=C2N (N ([C@]3 (N (C2=O) CCOC3) [H]) [C@H]4C=5C (CSC=6C4=CC=CC6) =C (F) C (F) =CC5) C=CC1=O
Molecular Formula
C24H20F2N3O7PS
Molecular Weight
563.47
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Cap-dependent endonuclease-IN-17
CAS Number2649362-71-8
PubChem CID163196324
IUPAC Name[(3R)-2-[(11S)-7,8-difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl]-9,12-dioxo-5-oxa-1,2,8-triazatricyclo[8.4.0.03,8]tetradeca-10,13-dien-11-yl] dihydrogen phosphate
Molecular FormulaC24H20F2N3O7PS
Molecular Weight563.5
XLogP-0.5
Topological Polar Surface Area145
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count12
Rotatable Bond Count3
Heavy Atom Count38
Formal Charge0
Complexity1100
SMILES
C1COC[C@@H]2N1C(=O)C3=C(C(=O)C=CN3N2[C@H]4C5=C(CSC6=CC=CC=C46)C(=C(C=C5)F)F)OP(=O)(O)O
InChI
InChI=1S/C24H20F2N3O7PS/c25-16-6-5-13-15(20(16)26)12-38-18-4-2-1-3-14(18)21(13)29-19-11-35-10-9-27(19)24(31)22-23(36-37(32,33)34)17(30)7-8-28(22)29/h1-8,19,21H,9-12H2,(H2,32,33,34)/t19-,21+/m1/s1
InChIKey
RBPQWOONNOYHLF-CTNGQTDRSA-N
Chemical Structure
2D Structure
2D structure of Cap-dependent endonuclease-IN-17
CAS: 2649362-71-8
CID: 163196324
Formula: C24H20F2N3O7PS
MW: 563.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight563.5
XLogP3-0.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count12
Rotatable Bond Count3
Exact Mass563.07276448
Monoisotopic Mass563.07276448
Topological Polar Surface Area145 Ų
Heavy Atom Count38
Formal Charge0
Complexity1100
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19213003-01Cap-dependent endonuclease-IN-7
GTR19185146-01Cap-dependent endonuclease-IN-8
GTR19184925-01Cap-dependent endonuclease-IN-23
GTR19184700-01Cap-dependent endonuclease-IN-5
GTR19186770-01Cap-dependent endonuclease-IN-26
GTR19185128-01Cap-dependent endonuclease-IN-13
GTR19184663-01Cap-dependent endonuclease-IN-14
GTR19184492Cap-dependent endonuclease-IN-3
GTR19262526-01Cap-dependent endonuclease-IN-28
GTR19185946-01Cap-dependent endonuclease-IN-19

Alternative Products

CatalogName
MBS5806645Cap-dependent endonuclease-IN-17
HY-143775Cap-dependent endonuclease-IN-20
HY-144067Cap-dependent endonuclease-IN-23
HY-143757Cap-dependent endonuclease-IN-10
HY-144068Cap-dependent endonuclease-IN-25
HY-143768Cap-dependent endonuclease-IN-14
HY-143750Cap-dependent endonuclease-IN-7
T64177-01Cap-dependent endonuclease-IN-2
T63808-01Cap-dependent endonuclease-IN-1
HY-143749Cap-dependent endonuclease-IN-6

Popular Products