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KIRA9

CAT: 0013-GTR19184555-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19184555-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KIRA9 is a potent IRE1 inhibitor with an IC50 of 4.8 μM in INS-1 cells, acting by competitively occupying the ATP-binding site. This mechanism blocks ER-associated mRNA decay and apoptosis, making it a valuable tool for studying ER stress in models of diabetes and neurodegenerative disease.
Field of Research
Cell Biology
Molecular Formula
C27H27F3N6O3S
Molecular Weight
572.6
Storage Conditions
-20°C
Notes
For research use only.

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