Products for Research Use Only
RegisterLogin

WDR5-47

CAT: 0013-GTR19184293-02Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19184293-02Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
WDR5-47 is a potent and selective small molecule inhibitor of the MLL1-WDR5 protein-protein interaction, exhibiting an IC50 of 0.3 μM. It is a valuable chemical probe for epigenetic research, enabling the study of MLL1 function and its role in leukemia in both cellular and biochemical assays.
CAS Number
1422389-91-0
Product Name Alternative
MLL1-WDR5, Histone Methyltransferase, HistoneMethyltransferase, WDR547, WDR5-47
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.08% (May vary between batches)
Solubility
DMSO:25 mg/mL (61.45 mM)
Smiles
N (C (=O) C1=C (Cl) C (C) =C (F) C=C1) C2=C (C=CC (N (=O) =O) =C2) N3CCN (C) CC3
Molecular Formula
C19H20ClFN4O3
Molecular Weight
406.84
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2-Chloro-4-fluoro-3-methyl-N-(2-(4-methylpiperazin-1-yl)-5-nitrophenyl)benzamide
CAS Number1422389-91-0
PubChem CID70679466
IUPAC Name2-chloro-4-fluoro-3-methyl-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide
Molecular FormulaC19H20ClFN4O3
Molecular Weight406.8
XLogP3.6
Topological Polar Surface Area81.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Heavy Atom Count28
Formal Charge0
Complexity570
SMILES
CC1=C(C=CC(=C1Cl)C(=O)NC2=C(C=CC(=C2)[N+](=O)[O-])N3CCN(CC3)C)F
InChI
InChI=1S/C19H20ClFN4O3/c1-12-15(21)5-4-14(18(12)20)19(26)22-16-11-13(25(27)28)3-6-17(16)24-9-7-23(2)8-10-24/h3-6,11H,7-10H2,1-2H3,(H,22,26)
InChIKey
QHWMIGPLLWYRIR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-Chloro-4-fluoro-3-methyl-N-(2-(4-methylpiperazin-1-yl)-5-nitrophenyl)benzamide
CAS: 1422389-91-0
CID: 70679466
Formula: C19H20ClFN4O3
MW: 406.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight406.8
XLogP33.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass406.1207964
Monoisotopic Mass406.1207964
Topological Polar Surface Area81.4 Ų
Heavy Atom Count28
Formal Charge0
Complexity570
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19243629-01WDR5-IN-6
GTR19261607-01WDR5-IN-8
GTR18912883WDR5 Peptide
GTR17939681WDR5 Antibody
GTR17922032-01WDR5 Antibody
GTR18586201-01WDR5 Antibody
GTR18304165WDR5 Antibody
GTR19184858-01WDR5-IN-5
GTR18118387-01WDR5 Antibody
GTR17888874-01WDR5 Antibody

Alternative Products

CatalogName
MBS5810292WDR5-47
bs-60233C-01WDR5-0103 --- WDR5 Inhibitor
030720WDR5
BA4986-10WDR5-IN-6
BA4987-25WDR5-0102
BA4836-5WDR5-IN-5
B4949-5.1WDR5 0103
BA2863-1WDR5-IN-1
70R-8499WDR5 antibody
HY-161123WDR5-IN-8

Popular Products