Products for Research Use Only

JAK3-IN-11

CAT: 0013-GTR19184201-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19184201-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JAK3-IN-11 is a potent, selective, and orally active covalent inhibitor of JAK3 (IC50 = 1.7 nM) . It blocks JAK3-dependent signaling and T-cell proliferation, making it a valuable research tool for investigating autoimmune disease mechanisms in both cellular and animal models.
CAS Number
2412734-00-8
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
N (C=1N=C (C=CN1) C2=CC=C (NC (C=C) =O) C=C2) C3=CC=C (C=C3) N4CCOCC4
Molecular Formula
C23H23N5O2
Molecular Weight
401.46
Storage Conditions
-20°C
Notes
For research use only.